<SEC-DOCUMENT>0001388171-12-000001.txt : 20120703
<SEC-HEADER>0001388171-12-000001.hdr.sgml : 20120703
<ACCEPTANCE-DATETIME>20120703171424
ACCESSION NUMBER:		0001388171-12-000001
CONFORMED SUBMISSION TYPE:	SC 13D/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20120703
DATE AS OF CHANGE:		20120703
GROUP MEMBERS:		CAXTON CORP
GROUP MEMBERS:		CXSYNTA LLC
GROUP MEMBERS:		KOVNER 2011-A INVESTMENT TRUST
GROUP MEMBERS:		KOVNER 2011-B INVESTMENT TRUST
GROUP MEMBERS:		KOVNER 2011-C INVESTMENT TRUST
GROUP MEMBERS:		KOVNER 2011-D INVESTMENT TRUST
GROUP MEMBERS:		KOVNER 2012-A SYNTA INVESTMENT TRUST
GROUP MEMBERS:		KOVNER 2012-B SYNTA INVESTMENT TRUST
GROUP MEMBERS:		KOVNER 2012-C SYNTA INVESTMENT TRUST
GROUP MEMBERS:		KOVNER 2012-D SYNTA INVESTMENT TRUST
GROUP MEMBERS:		MR. BRUCE S. KOVNER
GROUP MEMBERS:		MR. DAVID BEN-UR

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			SYNTA PHARMACEUTICALS CORP
		CENTRAL INDEX KEY:			0001157601
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000

	FILING VALUES:
		FORM TYPE:		SC 13D/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-82674
		FILM NUMBER:		12946049

	BUSINESS ADDRESS:	
		STREET 1:		45 HARTWELL AVE
		CITY:			LEXINGTON
		STATE:			MA
		ZIP:			02421
		BUSINESS PHONE:		781-274-8200

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CxSynta LLC
		CENTRAL INDEX KEY:			0001388171
		IRS NUMBER:				020604347
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13D/A

	BUSINESS ADDRESS:	
		STREET 1:		731 ALEXANDER ROAD
		STREET 2:		BUILDING 2
		CITY:			PRINCETON
		STATE:			NJ
		ZIP:			08540
		BUSINESS PHONE:		609-419-1800

	MAIL ADDRESS:	
		STREET 1:		731 ALEXANDER ROAD
		STREET 2:		BUILDING 2
		CITY:			PRINCETON
		STATE:			NJ
		ZIP:			08540
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13D/A
<SEQUENCE>1
<FILENAME>synta13damd4.txt
<DESCRIPTION>SC 13D - - SYNTA PHARMACEUTICALS AMEND 4
<TEXT>


			SECURITIES AND EXCHANGE COMMISSION
		     	     Washington, D.C. 20549

			          SCHEDULE 13D
		      Under the Securities Exchange Act of 1934

				(Amendment No. 4)

		     	    Synta Pharmaceuticals Corp.
		       		 (Name of Issuer)

			  	   Common Stock
		 	  (Title of Class of Securities)

				    87162T206
			          (CUSIP Number)

			     Mr. Scott B. Bernstein
			       Caxton Corporation
			   731 Alexander Road, Bldg. 2
			   Princeton, New Jersey 08540
			         (609) 419-1800
          (Name, Address and Telephone Number of Person Authorized to
                       Receive Notices and Communications)

			  	    6/29/2012
             (Date of Event which Requires Filing of this Statement)


If the filing person has previously filed a statement on Schedule 13G to
report the acquisition that is the subject of this Schedule 13D, and is
filing this schedule because of Section 240.13d-1(e), 240.13d-1(f) or
240.13d-1(g), check the following box. | |

Note:  Schedules filed in paper format shall include a signed original and
five copies of the schedule, including all exhibits.  See Section
240.13d-7 for other parties to whom copies are to be sent.

*The remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with respect to the subject class
of securities, and for any subsequent amendment containing information
which would alter disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be
deemed to be "filed" for the purpose of Section 18 of the Securities Exchange
Act of 1934 ("Act") or otherwise subject to the liabilities of that section of
the Act but shall be subject to all other provisions of the Act (however, see
the Notes).


 (1) Names of Reporting Persons.
     I.R.S. Identification Nos. of above persons (entities only).

    CxSynta LLC
    02-0604347

 (2) Check the Appropriate Box if a Member of a Group (See Instructions)  (a)|_|
                                                                          (b)|x|

 (3) SEC Use Only.

 (4) Source of Funds (See Instructions).
    WC

 (5) Check if Disclosure of Legal Proceedings is Required Pursuant to Items
     2(d) or 2(e)  |_|

 (6) Citizenship or Place of Organization
    Delaware

Number of Shares Beneficially Owned by Each Reporting Person With:

 (7) Sole Voting Power:
    0

 (8) Shared Voting Power:
    7,761,716

 (9) Sole Dispositive Power:
    0

 (10) Shared Dispositive Power:
    7,761,716

 (11) Aggregate Amount Beneficially Owned by Each Reporting Person.
    7,761,716

 (12) Check if the Aggregate Amount in Row (11) Excludes Certain Shares
      (see instructions).  |_|

 (13) Percent of Class Represented by Amount in Row (11).
     13.5%

 (14) Type of Reporting Person (See Instructions).
     OO

(1) Names of Reporting Persons.
     I.R.S. Identification Nos. of above persons (entities only).

    Caxton Corporation
    22-2437619

 (2) Check the Appropriate Box if a Member of a Group (See Instructions)  (a)|_|
                                                                          (b)|x|

 (3) SEC Use Only.

 (4) Source of Funds (See Instructions).
    AF

 (5) Check if Disclosure of Legal Proceedings is Required Pursuant to Items
     2(d) or 2(e)  |_|

 (6) Citizenship or Place of Organization
    Delaware

Number of Shares Beneficially Owned by Each Reporting Person With:

 (7) Sole Voting Power:
    0

 (8) Shared Voting Power:
    7,761,716

 (9) Sole Dispositive Power:
    0

 (10) Shared Dispositive Power:
    7,761,716

 (11) Aggregate Amount Beneficially Owned by Each Reporting Person.
    7,761,716

 (12) Check if the Aggregate Amount in Row (11) Excludes Certain Shares
      (see instructions).  |_|

 (13) Percent of Class Represented by Amount in Row (11).
     13.5%

 (14) Type of Reporting Person (See Instructions).
    CO

(1) Names of Reporting Persons.
     I.R.S. Identification Nos. of above persons (entities only).

    Kovner 2011-A Investment Trust

 (2) Check the Appropriate Box if a Member of a Group (See Instructions)  (a)|_|
                                                                          (b)|x|

 (3) SEC Use Only.

 (4) Source of Funds (See Instructions).
    OO

 (5) Check if Disclosure of Legal Proceedings is Required Pursuant to Items
     2(d) or 2(e)  |_|

 (6) Citizenship or Place of Organization
    New York

Number of Shares Beneficially Owned by Each Reporting Person With:

 (7) Sole Voting Power:
    125,000

 (8) Shared Voting Power:
    0

 (9) Sole Dispositive Power:
    125,000

 (10) Shared Dispositive Power:
    0

 (11) Aggregate Amount Beneficially Owned by Each Reporting Person.
    125,000

 (12) Check if the Aggregate Amount in Row (11) Excludes Certain Shares
      (see instructions).  |_|

 (13) Percent of Class Represented by Amount in Row (11).
     0.2%

 (14) Type of Reporting Person (See Instructions).
    OO


(1) Names of Reporting Persons.
     I.R.S. Identification Nos. of above persons (entities only).

    Kovner 2011-B Investment Trust

 (2) Check the Appropriate Box if a Member of a Group (See Instructions)  (a)|_|
                                                                          (b)|x|

 (3) SEC Use Only.

 (4) Source of Funds (See Instructions).
    OO

 (5) Check if Disclosure of Legal Proceedings is Required Pursuant to Items
     2(d) or 2(e)  |_|

 (6) Citizenship or Place of Organization
    New York

Number of Shares Beneficially Owned by Each Reporting Person With:

 (7) Sole Voting Power:
    125,000

 (8) Shared Voting Power:
    0

 (9) Sole Dispositive Power:
    125,000

 (10) Shared Dispositive Power:
    0

 (11) Aggregate Amount Beneficially Owned by Each Reporting Person.
    125,000

 (12) Check if the Aggregate Amount in Row (11) Excludes Certain Shares
      (see instructions).  |_|

 (13) Percent of Class Represented by Amount in Row (11).
     0.2%

 (14) Type of Reporting Person (See Instructions).
    OO

(1) Names of Reporting Persons.
     I.R.S. Identification Nos. of above persons (entities only).

    Kovner 2011-C Investment Trust

 (2) Check the Appropriate Box if a Member of a Group (See Instructions)  (a)|_|
                                                                          (b)|x|

 (3) SEC Use Only.

 (4) Source of Funds (See Instructions).
    OO

 (5) Check if Disclosure of Legal Proceedings is Required Pursuant to Items
     2(d) or 2(e)  |_|

 (6) Citizenship or Place of Organization
    New York

Number of Shares Beneficially Owned by Each Reporting Person With:

 (7) Sole Voting Power:
    125,000

 (8) Shared Voting Power:
    0

 (9) Sole Dispositive Power:
    125,000

 (10) Shared Dispositive Power:
    0

 (11) Aggregate Amount Beneficially Owned by Each Reporting Person.
    125,000

 (12) Check if the Aggregate Amount in Row (11) Excludes Certain Shares
      (see instructions).  |_|

 (13) Percent of Class Represented by Amount in Row (11).
     0.2%

 (14) Type of Reporting Person (See Instructions).
    OO

(1) Names of Reporting Persons.
     I.R.S. Identification Nos. of above persons (entities only).

    Kovner 2011-D Investment Trust

 (2) Check the Appropriate Box if a Member of a Group (See Instructions)  (a)|_|
                                                                          (b)|x|

 (3) SEC Use Only.

 (4) Source of Funds (See Instructions).
    OO

 (5) Check if Disclosure of Legal Proceedings is Required Pursuant to Items
     2(d) or 2(e)  |_|

 (6) Citizenship or Place of Organization
    New York

Number of Shares Beneficially Owned by Each Reporting Person With:

 (7) Sole Voting Power:
    125,000

 (8) Shared Voting Power:
    0

 (9) Sole Dispositive Power:
    125,000

 (10) Shared Dispositive Power:
    0

 (11) Aggregate Amount Beneficially Owned by Each Reporting Person.
    125,000

 (12) Check if the Aggregate Amount in Row (11) Excludes Certain Shares
      (see instructions).  |_|

 (13) Percent of Class Represented by Amount in Row (11).
     0.2%

 (14) Type of Reporting Person (See Instructions).
    OO

(1) Names of Reporting Persons.
     I.R.S. Identification Nos. of above persons (entities only).

    Kovner 2012-A Synta Investment Trust

 (2) Check the Appropriate Box if a Member of a Group (See Instructions)  (a)|_|
                                                                          (b)|x|

 (3) SEC Use Only.

 (4) Source of Funds (See Instructions).
    OO

 (5) Check if Disclosure of Legal Proceedings is Required Pursuant to Items
     2(d) or 2(e)  |_|

 (6) Citizenship or Place of Organization
    New York

Number of Shares Beneficially Owned by Each Reporting Person With:

 (7) Sole Voting Power:
    0

 (8) Shared Voting Power:
    475,000

 (9) Sole Dispositive Power:
    0

 (10) Shared Dispositive Power:
   475,000

 (11) Aggregate Amount Beneficially Owned by Each Reporting Person.
    475,000

 (12) Check if the Aggregate Amount in Row (11) Excludes Certain Shares
      (see instructions).  |_|

 (13) Percent of Class Represented by Amount in Row (11).
     0.8%

 (14) Type of Reporting Person (See Instructions).
    OO

(1) Names of Reporting Persons.
     I.R.S. Identification Nos. of above persons (entities only).

    Kovner 2012-B Synta Investment Trust

 (2) Check the Appropriate Box if a Member of a Group (See Instructions)  (a)|_|
                                                                          (b)|x|

 (3) SEC Use Only.

 (4) Source of Funds (See Instructions).
    OO

 (5) Check if Disclosure of Legal Proceedings is Required Pursuant to Items
     2(d) or 2(e)  |_|

 (6) Citizenship or Place of Organization
    New York

Number of Shares Beneficially Owned by Each Reporting Person With:

 (7) Sole Voting Power:
    0

 (8) Shared Voting Power:
    475,000

 (9) Sole Dispositive Power:
    0

 (10) Shared Dispositive Power:
    475,000

 (11) Aggregate Amount Beneficially Owned by Each Reporting Person.
    475,000

 (12) Check if the Aggregate Amount in Row (11) Excludes Certain Shares
      (see instructions).  |_|

 (13) Percent of Class Represented by Amount in Row (11).
     0.8%

 (14) Type of Reporting Person (See Instructions).
    OO

(1) Names of Reporting Persons.
     I.R.S. Identification Nos. of above persons (entities only).

    Kovner 2012-C Synta Investment Trust

 (2) Check the Appropriate Box if a Member of a Group (See Instructions)  (a)|_|
                                                                          (b)|x|

 (3) SEC Use Only.

 (4) Source of Funds (See Instructions).
    OO

 (5) Check if Disclosure of Legal Proceedings is Required Pursuant to Items
     2(d) or 2(e)  |_|

 (6) Citizenship or Place of Organization
    New York

Number of Shares Beneficially Owned by Each Reporting Person With:

 (7) Sole Voting Power:
    0

 (8) Shared Voting Power:
    475,000

 (9) Sole Dispositive Power:
    0

 (10) Shared Dispositive Power:
    475,000

 (11) Aggregate Amount Beneficially Owned by Each Reporting Person.
    475,000

 (12) Check if the Aggregate Amount in Row (11) Excludes Certain Shares
      (see instructions).  |_|

 (13) Percent of Class Represented by Amount in Row (11).
     0.8%

 (14) Type of Reporting Person (See Instructions).
    OO

(1) Names of Reporting Persons.
     I.R.S. Identification Nos. of above persons (entities only).

    Kovner 2012-D Synta Investment Trust

 (2) Check the Appropriate Box if a Member of a Group (See Instructions)  (a)|_|
                                                                          (b)|x|

 (3) SEC Use Only.

 (4) Source of Funds (See Instructions).
    OO

 (5) Check if Disclosure of Legal Proceedings is Required Pursuant to Items
     2(d) or 2(e)  |_|

 (6) Citizenship or Place of Organization
    New York

Number of Shares Beneficially Owned by Each Reporting Person With:

 (7) Sole Voting Power:
    0

 (8) Shared Voting Power:
    475,000

 (9) Sole Dispositive Power:
    0

 (10) Shared Dispositive Power:
    475,000

 (11) Aggregate Amount Beneficially Owned by Each Reporting Person.
    475,000

 (12) Check if the Aggregate Amount in Row (11) Excludes Certain Shares
      (see instructions).  |_|

 (13) Percent of Class Represented by Amount in Row (11).
     0.8%

 (14) Type of Reporting Person (See Instructions).
    OO

(1) Names of Reporting Persons.
     I.R.S. Identification Nos. of above persons (entities only).

    Ben-Ur, David

 (2) Check the Appropriate Box if a Member of a Group (See Instructions)  (a)|_|
                                                                          (b)|x|

 (3) SEC Use Only.

 (4) Source of Funds (See Instructions).
    PF

 (5) Check if Disclosure of Legal Proceedings is Required Pursuant to Items
     2(d) or 2(e)  |_|

 (6) Citizenship or Place of Organization
    United States

Number of Shares Beneficially Owned by Each Reporting Person With:

 (7) Sole Voting Power:
    2,700

 (8) Shared Voting Power:
    0

 (9) Sole Dispositive Power:
    2,700

 (10) Shared Dispositive Power:
    0

 (11) Aggregate Amount Beneficially Owned by Each Reporting Person.
    2,700

 (12) Check if the Aggregate Amount in Row (11) Excludes Certain Shares
      (see instructions).  |_|

 (13) Percent of Class Represented by Amount in Row (11).
     0.0%

 (14) Type of Reporting Person (See Instructions).
     IN

(1) Names of Reporting Persons.
     I.R.S. Identification Nos. of above persons (entities only).

    Kovner, Bruce

 (2) Check the Appropriate Box if a Member of a Group (See Instructions)  (a)|_|
                                                                          (b)|x|

 (3) SEC Use Only.

 (4) Source of Funds (See Instructions).
    AF,PF

 (5) Check if Disclosure of Legal Proceedings is Required Pursuant to Items
     2(d) or 2(e)  |_|

 (6) Citizenship or Place of Organization
    United States

Number of Shares Beneficially Owned by Each Reporting Person With:

 (7) Sole Voting Power:
    5,001,875

 (8) Shared Voting Power:
    9,661,716

 (9) Sole Dispositive Power:
    5,001,875

 (10) Shared Dispositive Power:
    9,661,716

 (11) Aggregate Amount Beneficially Owned by Each Reporting Person.
    14,663,591

 (12) Check if the Aggregate Amount in Row (11) Excludes Certain Shares
      (see instructions).  |_|

 (13) Percent of Class Represented by Amount in Row (11).
     25.4%

 (14) Type of Reporting Person (See Instructions).
     IN


Item 3.  Source and Amount of Funds or Other Consideration

     Item 3 is hereby amended by adding the following thereto:

      Mr. Kovner has expended, in aggregate, approximately $36,763,958
      (excluding commissions, if any) to acquire 7,272,816 shares of
      Synta Pharmaceuticals Corp.  The purchase price for the shares of
      Common Stock acquired by Mr. Kovner was paid out of Mr. Kovner's
      personal funds.  52,372 of the outstanding shares of Common Stock
      directly owned by Mr. Kovner were issued to Mr. Kovner as
      compensation for his service on the Company's Board of Directors
      or certain of its committees.  Mr. Kovner also was granted
      76,687 options on the Common Stock of the Company as compensation in
      connection with his service on the Company's Board of Directors.

      Mr. David Ben-Ur has expended, in aggregate, approximately
      $14,678 (excluding commissions) to acquire 2,700 shares of the
      Company.

      Each of the trusts listed herein have received their respective
      shares of Common Stock of the Company as gifts from Mr. Kovner.


Item 5.  Interest in Securities of the Issuer

     Subparagraph (a), (b) and (c) of Item 5 of the Schedule 13D is
     hereby amended and replaced by the following:

(a)  (i) CxSynta LLC beneficially owns 7,761,716 shares of Common Stock,
      representing approximately 13.5% of the 57,639,108 shares of Common
      Stock reported to be outstanding as of April 30, 2012, as reported
      in the Company's Form 10-Q filed with the Securities Exchange
      Commission on May 3, 2012. The percentages used herein and in the
      rest of this Amendment No. 4 are calculated based upon such number
      of outstanding shares.

     (ii) Caxton Corporation is the managing member of CxSynta LLC and as
      such, has voting and dispositive power with respect to the 7,761,716
      shares beneficially owned by CxSynta LLC.  As a result, Caxton
      Corporation may be deemed to beneficially own 7,761,716 shares of
      Common Stock, representing approximately 13.5% of the total shares
      of Common Stock issued and outstanding.

     (iii) Kovner 2011-A Investment Trust beneficially owns 125,000 shares
     of Common Stock, representing approximately 0.2% of the total shares of
     Common Stock issued and outstanding.

     (iv)  Kovner 2011-B Investment Trust beneficially owns 125,000 shares
     of Common Stock, representing approximately 0.2% of the total shares of
     Common Stock issued and outstanding.

     (v)   Kovner 2011-C Investment Trust beneficially owns 125,000 shares
     of Common Stock, representing approximately 0.2% of the total shares of
     Common Stock issued and outstanding.

     (vi)  Kovner 2011-D Investment Trust beneficially owns 125,000 shares
     of Common Stock, representing approximately 0.2% of the total shares of
     Common Stock issued and outstanding.

     (vii) Kovner 2012-A Synta Investment Trust beneficially owns 475,000
     shares of Common Stock, representing approximately 0.8% of the total
     shares ofCommon Stock issued and outstanding.

     (viii)Kovner 2012-B Synta Investment Trust beneficially owns 475,000
     shares of Common Stock, representing approximately 0.8% of the total
     shares ofCommon Stock issued and outstanding.

     (ix)  Kovner 2012-C Synta Investment Trust beneficially owns 475,000
     shares of Common Stock, representing approximately 0.8% of the total
     shares of Common Stock issued and outstanding.

     (x)   Kovner 2012-D Synta Investment Trust beneficially owns 475,000
     shares of Common Stock, representing approximately 0.8% of the total
     shares of Common Stock issued and outstanding.

     (xi) Mr. Ben-Ur is the Chief Investment Officer of Caxton Alternative
      Management LP and has sole beneficial ownership of 2,700 shares of
      Common Stock, representing approximately 0.0% of the total shares of
      Common Stock issued and outstanding.

     (xii) Mr. Kovner has sole beneficial ownership of 5,001,875 shares of
      Common Stock, which includes options to purchase 76,687 shares of
      Common Stock upon the exercise of such options.  In addition, Mr. Kovner
      is the Chairman and sole shareholder of Caxton Corporation, the managing
      member of CxSynta LLC, and as a result may be deemed to beneficially
      own the securities of the Company owned by CxSynta LLC.  Mr. Kovner is
      the sole trustee of each of the following trusts and as a result may be
      deemed to beneficially own the 1,900,000 securities of the Company owned
      by such trusts in aggregate: Kovner 2012-A Synta Investment Trust; Kovner
      2012-B Synta Investment Trust; Kovner 2012-C Synta Investment Trust; and
      Kovner 2012-D Synta Investment Trust.  Mr. Kovner disclaims beneficial
      ownership of the shares of Common Stock owned directly by CxSynta LLC
      except to the extent of his pecuniary interest therein.  Mr. Kovner
      also disclaims beneficial ownership of the shares of Common Stock directly
      owned by such trusts. As a result of the foregoing, Mr. Kovner may be
      deemed to beneficially own an aggregate of 14,663,591 shares of Common
      Stock, representing approximately 25.4% of the total shares of Common
      Stock issued and outstanding.

(b)   Caxton Corporation and Mr. Kovner, as Chairman and sole shareholder of
      Caxton Corporation, the managing member of CxSynta LLC, may be deemed to
      share voting and dispositive power over 7,761,716 shares of Common Stock
      owned directly by CxSynta LLC.  Cadence Trust Company, the Trustee of
      each of the following trusts, has sole voting and dispositive power
      over the aggregate 500,000 shares of Common Stock owned directly
      by each of such Trusts:  Kovner 2011-A Investment Trust, Kovner
      2011-B Investment Trust, Kovner 2011-C Investment Trust, and Kovner
      2011-D Investment Trust.  While Mr. Kovner is a director of Cadence Trust
      Company and, as such, may be deemed to not have beneficial ownership over
      the shares of the Company held by the trusts for which Cadence Trust
      Company serves as Trustee, disclosure of such relationship and ownership
      is being made herein. Mr. Ben-Ur has sole voting and dispositive power
      over the 2,700 shares of Common Stock owned directly by him.  Mr. Kovner
      also may be deemed to share voting and dispositive power with respect to
      the 1,900,000 shares of Common Stock of the Company that are owned by
      each of the following trusts, as Mr. Kovner is the Trustee of such
      Trusts:  Kovner 2012-A Synta Investment Trust, Kovner 2012-B Synta
      Investment Trust, Kovner 2012-C Synta Investment Trust, and Kovner
      2012-D Synta Investment Trust.  In addition, Mr. Kovner has sole
      voting and dispositive power with respect to the 5,001,875 shares of
      Common Stock which he directly beneficially owns.

(c)   On June 29, 2012, Mr. Kovner purchased 910,000 shares of Common Stock
      at a weighted average purchase price of $5.4498 per share.  On June 29,
      2012, Mr. Ben-Ur purchased 2,700 shares of Common Stock of the Company
      at an average cost of $5.45.  On June 29, 2012, Mr. Kovner transferred,
      as gifts, 475,000 shares of Common Stock of the Company to each of the
      following trusts (for an aggregate 1,900,000 shares of Common Stock of
      the Company):  Kovner 2012-A Synta Investment Trust, Kovner 2012-B Synta
      Investment Trust, Kovner 2012-C Synta Investment Trust, and Kovner 2012-D
      Synta Investment Trust.  On July 1, 2012, Mr. Kovner received shares of
      Common Stock of the Company in the amounts of (a) 7,312, (b) 914, and
      (c) 914, and 10,000 options on Common Stock of the Company, as
      compensation for his service on the Company's Board of Directors or on
      certain of its committees.

      Except as reported in this statement on Schedule 13D, the Reporting
      Persons are not believed to have engaged in any other transactions in the
      Company's securities in the past sixty (60) days.


Item 6.  Contracts, Arrangements, Understandings or Relationships
         with Respect to Securities of the Issuer.

      Item 6 is hereby amended by adding the following thereto:

      The information contained in Item 5 of this Amendment No.4 is
      incorporated by reference.

      Mr. Ben-Ur serves as Chief Investment Officer of Caxton Alternative
      Management LP, an entity indirectly controlled by Mr. Kovner and as such
      has agreed, during the course of his employment with Caxton Alternative
      Management LP, to abide by certain policies and procedures applicable to
      Mr. Kovner as a director of the Company.  By reason of this agreement,
      Mr. Kovner and Mr. Ben-Ur may be deemed to be members of a group.
      Mr. Kovner, Mr. Ben-Ur and all other Reporting Persons named herein,
      expressly disclaim beneficial ownership of the Common Stock of the other
      Reporting Persons except to the extent they may have an interest in such
      other Reporting Person.

      Except as set forth above, there are no contracts, arrangements,
      understandings or relationships (legal or otherwise) among the persons
      filing this Report or the Listed Persons or between such persons and
      any other person with respect to any securities of the Company,
      including, but not limited to transfer or voting of any of the
      securities, finder's fees, joint ventures, loan or option
      arrangements, puts or calls, guarantees of profits, division of profits
      or losses, or the giving or withholding of proxies.

Item 7.  Material to Be Filed as Exhibits


Signature


After reasonable inquiry and to the best of my knowledge and belief, I certify
that the information set forth in this statement is true, complete and correct.

					CxSynta LLC

Date: 07/03/2012			By Caxton Corporation, Managing Member
	                                of CxSynta LLC,
                                        by /s/ Scott B. Bernstein,
					Secretary of Caxton Corporation

					Caxton Corporation

Date: 07/03/2012			/s/ Scott B. Bernstein, Secretary of
					Caxton Corporation


Date: 07/03/2012			Kovner 2011-A Investment Trust

					/s/ Peter P. D'Angelo, President of
					Cadence Trust Company, Trustee

Date: 07/03/2012			Kovner 2011-B Investment Trust

					/s/ Peter P. D'Angelo, President of
					Cadence Trust Company, Trustee

Date: 07/03/2012			Kovner 2011-C Investment Trust

					/s/ Peter P. D'Angelo, President of
					Cadence Trust Company, Trustee

Date: 07/03/2012			Kovner 2011-D Investment Trust

					/s/ Peter P. D'Angelo, President of
					Cadence Trust Company, Trustee

Date: 07/03/2012			Kovner 2012-A Synta Investment Trust

					/s/ Bruce S. Kovner, Trustee

Date: 07/03/2012			Kovner 2012-B Synta Investment Trust

					/s/ Bruce S. Kovner, Trustee

Date: 07/03/2012			Kovner 2012-C Synta Investment Trust

					/s/ Bruce S. Kovner, Trustee

Date: 07/03/2012			Kovner 2012-D Synta Investment Trust

					/s/ Bruce S. Kovner, Trustee

Date: 07/03/2012			David Ben-Ur
                                        /s/ David Ben-Ur

					Bruce S. Kovner
Date: 07/03/2012			/s/ Bruce S. Kovner


The original statement shall be signed by each person on whose behalf the
statement is filed or his authorized representative. If the statement is
signed on behalf of a person by his authorized representative (other than
an executive officer or general partner of the filing person), evidence of
the representative's authority to sign on behalf of such person shall be
filed with the statement: provided, however, that a power of attorney for
this purpose which is already on file with the Commission may be incorporated
by reference.  The name and any title of each person who signs the statement
shall be typed or printed beneath his signature.

ATTENTION: Intentional misstatements or omissions of fact constitute Federal
criminal violations (See 18 U.S.C. 1001).


</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>